diff --git a/dangerzone/gui/__init__.py b/dangerzone/gui/__init__.py
index c62cf23..386ecf5 100644
--- a/dangerzone/gui/__init__.py
+++ b/dangerzone/gui/__init__.py
@@ -35,8 +35,10 @@ class ApplicationWrapper(QtCore.QObject):
         def monkeypatch_event(event):
             # In macOS, handle the file open event
             if event.type() == QtCore.QEvent.FileOpen:
-                self.document_selected.emit(event.file())
-                return True
+                # Skip file open events in dev mode
+                if not sys.dangerzone_dev:
+                    self.document_selected.emit(event.file())
+                    return True
             elif event.type() == QtCore.QEvent.ApplicationActivate:
                 self.application_activated.emit()
                 return True